Functional Neuroimaging to Investigate Anticholinesterase Therapy in Alzheimer's Disease

Functional Neuroimaging in Parkinson’s Disease

The use of functional imaging in neurodegenerative diseases has increased in recent years, with applications in research into the underlying pathophysiology, aiding in diagnosis, or evaluating new treatments. In Parkinson’s disease (PD), these imaging methods have expanded our understanding of the disease beyond dopaminergic deficits. Moreover, functional imaging methods have described alterati...

Functional neuroimaging in Parkinson's disease.

INTRODUCTION Functional neuroimaging techniques have greatly contributed to improving our understanding of Parkinson's disease (PD) neurodegeneration and related compensatory mechanisms. AREAS COVERED In this paper, the authors analyze the role of functional neuroimaging as a diagnostic tool in PD and review functional neuroimaging studies on PD progression and compensatory adaptations. Throu...

Introduction to Functional Neuroimaging

Handbook of Functional Neuroimaging Chapter 1 INTRODUCTION TO FUNCTIONAL NEUROIMAGING

There has been explosive interest in the use of brain imaging to study cognitive and affective processes in recent years. Examine Figure 1, for example, to see the dramatic rise in numbers of publications from 1992 to 1999 in which the term, " functional Magnetic Resonance Imaging " (fMRI) appears in the title. Because of the surge of empirical work that now relies on a combination of behaviora...

Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease.

BACKGROUND Anticholinesterase therapies offer modest benefit to subgroups of AD sufferers. However, there has previously been no way of predicting which patients will respond to any of the drugs. OBJECTIVE To discover if gender and/or apolipoprotein E genotype can be used as predictors of response in the clinical setting. DESIGN 107 patients from the Bristol Memory Disorders Clinic took par...